calc hfa icos raf mek derived

api.magentlab.comOther derived

POST https://api.magentlab.com/api/calc/hfa_icos_raf_mek

passlisted in Coinbase#229 by calls of 844 on this host

0.005 USDC

per call, as the listing declares it on eip155:8453

Compare with another Every figure as JSON Cite this page

the price, as of 2026-10-13 00:37 UTC · method · pinnable

Validation state: pass; as of 2026-10-12 11:43 UTC · method · pinnable · sweep daily-2026-10-12
Uptime, 7 / 30 / 90 days: 100% / 100% / 100%; as of 2026-10-12 11:43 UTC · method · pinnable · 7 of 7 in 7d, 15 of 15 in 30d, 15 of 15 in 90d
Calls, trailing 30 days: 4; as of 2026-10-13 00:37 UTC · method · pinnable
Unique payers, trailing 30 days: 2; as of 2026-10-13 00:37 UTC · method · pinnable
Last called: 2026-10-12 13:35 UTC; as of 2026-10-13 00:37 UTC · method · pinnable
First observed by TOLLderived: 2026-09-28; as of 2026-09-28 13:51 UTC · method · pinnable · observation began 10 September 2026; listings that predate it show that date
Pricederived: 0.005 USDC; as of 2026-10-13 00:37 UTC · method · pinnable · on eip155:8453
Networks: 1; as of 2026-10-13 00:37 UTC · method · pinnable

Counters

40 observations, 5 of them a change

How has the volume on this endpoint moved?

Calls counted in the trailing 30 days on this endpoint, at every snapshot since 2026-09-28. Each point is a trailing-30-day sum as the registry published it, not a daily rate. The axis is truncated to the range of the data with a break at its foot.

In words

calc hfa icos raf mek shares api.magentlab.com with 843 other listed endpoints and is tied 229th by calls with 522 others.

Callers of calc hfa icos raf mek supply a JSON body with the field items.

Its example response has the fields path, count and items.

calc hfa icos raf mek drew 4 calls from 2 unique payers in the trailing 30 days.

The last call to calc hfa icos raf mek came on the day of the snapshot, 2026-10-12.

Each call is priced at 0.005 USDC, payable on Base.

calc hfa icos raf mek, a POST endpoint on api.magentlab.com, appears in the Coinbase registry; TOLL's taxonomy puts it in the "other" category.

calc hfa icos raf mek answered the sweep of 2026-10-12 with a valid 402, as at every sweep since 2026-09-28.

Closest in price to calc hfa icos raf mek within the "other" category: ping at www.api-xpay.com and aviation airport status at api.x402node.dev.

calc hfa icos raf mek is priced above 31% of comparable listings in the "other" category.

calc hfa icos raf mek out-counts 66% of the 3,795 endpoints in the "other" category that carry counters.

The wallet paid by calc hfa icos raf mek is the payee of 844 endpoints on one host.

The seller's own tags are hfa-icos, raf-mek, cardio-oncology and lyon-2020.

calc hfa icos raf mek dropped out of the registry at the pull of 2026-09-30 and was listed again on 2026-09-30.

The price of calc hfa icos raf mek is declared by 773 other listings in the "other" category too.

Payment options as declared

the payment options, as of 2026-10-13 00:37 UTC · method · pinnable

Every payment option declared on this listing
registry	network	asset	amount	scheme	pay to
Coinbase	eip155:8453	USDC	0.005 USDC	exact	0x836Be2…c19Ee2

Preflight checks at the last sweep

the checks, as of 2026-10-12 11:43 UTC · method · pinnableendpoint answered HTTP 402

No named check failed.

Validation history, 90 days

Every sweep that observed this endpoint, newest first.

Validation observations over the last 90 days
observed, UTC	state	sweep
2026-10-12 11:43 UTC	pass	daily-2026-10-12
2026-10-11 10:22 UTC	pass	daily-2026-10-11
2026-10-10 18:33 UTC	pass	daily-2026-10-10
2026-10-09 11:59 UTC	pass	daily-2026-10-09
2026-10-08 13:49 UTC	pass	daily-2026-10-08
2026-10-07 12:51 UTC	pass	daily-2026-10-07
2026-10-06 13:31 UTC	pass	daily-2026-10-06
2026-10-05 11:52 UTC	pass	daily-2026-10-05
2026-10-04 14:30 UTC	pass	daily-2026-10-04
2026-10-03 07:46 UTC	pass	daily-2026-10-03
2026-10-02 16:54 UTC	pass	daily-2026-10-02
2026-10-01 09:35 UTC	pass	daily-2026-10-01
2026-09-30 09:03 UTC	pass	daily-2026-09-30
2026-09-29 21:08 UTC	pass	daily-2026-09-29
2026-09-28 16:49 UTC	pass	new-after-daily-2026-09-28

Registry presence

Presence in a registry, not liveness of the service (method). Newest first.

2026-09-30 22:14 UTCback in Coinbase
2026-09-30 12:32 UTCabsent from Coinbase at this pull
2026-09-28 13:51 UTClisted in Coinbase

Declared input and output, as listed

From the registry record, not validated by TOLL.the declared schema, as of 2026-10-12 13:35 UTC · method · live

The input and output block

{
  "input": {
    "body": {
      "items": [
        {
          "ckd": false,
          "obesity": false,
          "diabetes": false,
          "age_years": 50,
          "arrhythmia": false,
          "mi_or_cabg": false,
          "elevated_bnp": false,
          "hypertension": false,
          "lvef_percent": 60,
          "stable_angina": false,
          "elevated_troponin": false,
          "prior_anthracycline": false,
          "current_or_significant_smoker": false,
          "severe_valvular_heart_disease": false,
          "heart_failure_or_cardiomyopathy": false,
          "prior_left_chest_or_mediastinal_rt": false
        },
        {
          "ckd": false,
          "obesity": false,
          "diabetes": false,
          "age_years": 50,
          "arrhythmia": false,
          "mi_or_cabg": false,
          "elevated_bnp": false,
          "hypertension": false,
          "lvef_percent": 60,
          "stable_angina": false,
          "elevated_troponin": false,
          "prior_anthracycline": false,
          "current_or_significant_smoker": false,
          "severe_valvular_heart_disease": false,
          "heart_failure_or_cardiomyopathy": false,
          "prior_left_chest_or_mediastinal_rt": false
        }
      ]
    },
    "type": "http",
    "method": "POST"
  },
  "output": {
    "type": "json",
    "example": {
      "path": "/api/calc/hfa_icos_raf_mek",
      "count": 2,
      "items": [
        {
          "formula": "hfa_icos_raf_mek",
          "citation": {
            "id": "lyon-2020",
            "doi": "10.1002/ejhf.1920",
            "pmid": "32458582",
            "title": "Baseline cardiovascular risk assessment in cancer patients scheduled to receive cardiotoxic cancer therapies: a position statement and new risk assessment tools from the Cardio-Oncology Study Group of the Heart Failure Association of the European Society of Cardiology in collaboration with the International Cardio-Oncology Society",
            "source": "Eur J Heart Fail. 2020;22(11):1945-1960",
            "authors": "Lyon AR, Dent S, Stanway S, et al."
          },
          "age_years": 50,
          "components": [
            {
              "tier": "very_high",
              "factor": "heart_failure_or_cardiomyopathy",
              "points": 0,
              "present": false
            },
            {
              "tier": "high",
              "factor": "mi_or_cabg",
              "points": 0,
              "present": false
            },
            {
              "tier": "high",
              "factor": "stable_angina",
              "points": 0,
              "present": false
            },
            {
              "tier": "high",
              "factor": "severe_valvular_heart_disease",
              "points": 0,
              "present": false
            },
            {
              "tier": "medium",
              "value": 60,
              "factor": "lvef_50_54",
              "points": 0,
              "present": false
            },
            {
              "tier": "medium",
              "factor": "arrhythmia",
              "points": 0,
              "present": false
            },
            {
              "tier": "medium",
              "factor": "elevated_troponin",
              "points": 0,
              "present": false
            },
            {
              "tier": "medium",
              "factor": "elevated_bnp",
              "points": 0,
              "present": false
            },
            {
              "tier": "medium",
              "value": 50,
              "factor": "age_ge_65",
              "points": 0,
              "present": false
            },
            {
              "tier": "medium",
              "factor": "hypertension",
              "points": 0,
              "present": false
            },
            {
              "tier": "medium",
              "factor": "diabetes",
              "points": 0,
              "present": false
            },
            {
              "tier": "medium",
              "factor": "ckd",
              "points": 0,
              "present": false
            },
            {
              "tier": "high",
              "factor": "prior_anthracycline",
              "points": 0,
              "present": false
            },
            {
              "tier": "medium",
              "factor": "prior_left_chest_or_mediastinal_rt",
              "points": 0,
              "present": false
            },
            {
              "tier": "medium",
              "factor": "current_or_significant_smoker",
              "points": 0,
              "present": false
            },
            {
              "tier": "medium",
              "factor": "obesity",
              "points": 0,
              "present": false
            }
          ],
          "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
          "risk_level": "low",
          "lvef_percent": 60,
          "medium_points": 0,
          "formula_expression": "HFA-ICOS RAF-MEK (Lyon 2020): very_high if heart_failure_or_cardiomyopathy; high if mi_or_cabg or stable_angina or severe_valvular_heart_disease or prior_anthracycline or medium_points>=5; medium if medium_points 2-4; low if medium_points 0-1; medium_points = M2 (lvef 50-54, elevated_troponin, elevated_bnp, hypertension, prior_left_chest_or_mediastinal_rt) + M1 (arrhythmia, age>=65, diabetes, ckd, current_or_significant_smoker, obesity); LVEF <50 is not a printed High row on this table; age>=65 Medium 1 only (no High age band); cardiotoxicity_guide low <2%, medium 2-9%, high 10-19%, very_high >=20%",
          "cardiotoxicity_guide": "<2%"
        },
        {
          "formula": "hfa_icos_raf_mek",
          "citation": {
            "id": "lyon-2020",
            "doi": "10.1002/ejhf.1920",
            "pmid": "32458582",
            "title": "Baseline cardiovascular risk assessment in cancer patients scheduled to receive cardiotoxic cancer therapies: a position statement and new risk assessment tools from the Cardio-Oncology Study Group of the Heart Failure Association of the European Society of Cardiology in collaboration with the International Cardio-Oncology Society",
            "source": "Eur J Heart Fail. 2020;22(11):1945-1960",
            "authors": "Lyon AR, Dent S, Stanway S, et al."
          },
          "age_years": 50,
          "components": [
            {
              "tier": "very_high",
              "factor": "heart_failure_or_cardiomyopathy",
              "points": 0,
              "present": false
            },
            {
              "tier": "high",
              "factor": "mi_or_cabg",
              "points": 0,
              "present": false
            },
            {
              "tier": "high",
              "factor": "stable_angina",
              "points": 0,
              "present": false
            },
            {
              "tier": "high",
              "factor": "severe_valvular_heart_disease",
              "points": 0,
              "present": false
            },
            {
              "tier": "medium",
              "value": 60,
              "factor": "lvef_50_54",
              "points": 0,
              "present": false
            },
            {
              "tier": "medium",
              "factor": "arrhythmia",
              "points": 0,
              "present": false
            },
            {
              "tier": "medium",
              "factor": "elevated_troponin",
              "points": 0,
              "present": false
            },
            {
              "tier": "medium",
              "factor": "elevated_bnp",
              "points": 0,
              "present": false
            },
            {
              "tier": "medium",
              "value": 50,
              "factor": "age_ge_65",
              "points": 0,
              "present": false
            },
            {
              "tier": "medium",
              "factor": "hypertension",
              "points": 0,
              "present": false
            },
            {
              "tier": "medium",
              "factor": "diabetes",
              "points": 0,
              "present": false
            },
            {
              "tier": "medium",
              "factor": "ckd",
              "points": 0,
              "present": false
            },
            {
              "tier": "high",
              "factor": "prior_anthracycline",
              "points": 0,
              "present": false
            },
            {
              "tier": "medium",
              "factor": "prior_left_chest_or_mediastinal_rt",
              "points": 0,
              "present": false
            },
            {
              "tier": "medium",
              "factor": "current_or_significant_smoker",
              "points": 0,
              "present": false
            },
            {
              "tier": "medium",
              "factor": "obesity",
              "points": 0,
              "present": false
            }
          ],
          "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
          "risk_level": "low",
          "lvef_percent": 60,
          "medium_points": 0,
          "formula_expression": "HFA-ICOS RAF-MEK (Lyon 2020): very_high if heart_failure_or_cardiomyopathy; high if mi_or_cabg or stable_angina or severe_valvular_heart_disease or prior_anthracycline or medium_points>=5; medium if medium_points 2-4; low if medium_points 0-1; medium_points = M2 (lvef 50-54, elevated_troponin, elevated_bnp, hypertension, prior_left_chest_or_mediastinal_rt) + M1 (arrhythmia, age>=65, diabetes, ckd, current_or_significant_smoker, obesity); LVEF <50 is not a printed High row on this table; age>=65 Medium 1 only (no High age band); cardiotoxicity_guide low <2%, medium 2-9%, high 10-19%, very_high >=20%",
          "cardiotoxicity_guide": "<2%"
        }
      ]
    }
  }
}

What the listing says

Lyon 2020 HFA-ICOS baseline CV risk before combination RAF and MEK inhibitors. Very high if heart failure or cardiomyopathy; High if MI/CABG, stable angina, severe valvular disease, prior anthracycline, or ≥5 medium points; Medium if 2-4 medium points; Low if 0-1. Age ≥65 is Medium 1 only. LVEF 50-54 is Medium 2; this table has no printed LVEF <50 High row. Expert-opinion cardiotoxicity guide <2% / 2-9% / 10-19% / ≥20%. Not a treatment order.

the record, 2026-10-12 13:35 UTC · method · pinnable

As declared

POST
eip155:8453
USDC
exact

Every tag is a field on the listing, not a keyword TOLL assigned.

Who is paid

0x836Be2…c19Ee2

Takes payment for 844 endpoints on 1 host.

Among Other

counted above66%

of 3,795 that carry counters

cheaper than31%

of 3,795 with a comparable price

3,868 endpoints are in this category. 773 declare exactly this price.

the comparison, 2026-10-13 00:37 UTC · method · live

Nearest on price

enrich profilewin.oneshotagent.com0.005 USDCpass
pingwww.api-xpay.com0.005 USDCpass
aviation airport statusapi.x402node.dev0.005 USDCpass
ethagent.pocket.network0.005 USDCpass
fetchnanoparse.app0.005 USDCpass

Same category, nearest declared price, one per payee wallet (method). the list, 2026-10-13 00:37 UTC · method · live

Elsewhere in the record

Cite this page

The pinned URL below renders this page from the snapshot of 2026-10-13 00:37 UTC and does not change; the live page does, every six hours. Data reuse is under CC BY 4.0 (terms).

Plain text

TOLL, "calc hfa icos raf mek on api.magentlab.com", snapshot of 2026-10-13 00:37 UTC. https://tollindex.com/e/api-magentlab-com-api-calc-hfa-icos-raf-mek-d84f44/at/2026-10-13T00-37Z. Accessed [access date].

BibTeX

@misc{toll-e-api-magentlab-com-api-calc-hfa-icos-raf-mek-d84f44-2026-10-13T00-37Z,
  author = {TOLL},
  title = {calc hfa icos raf mek on api.magentlab.com},
  howpublished = {\url{https://tollindex.com/e/api-magentlab-com-api-calc-hfa-icos-raf-mek-d84f44/at/2026-10-13T00-37Z}},
  year = {2026},
  month = {10},
  note = {Pinned view of the snapshot of 2026-10-13 00:37 UTC. Accessed [access date].}
}

Reports and replies about this endpoint

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