{"api":"v1","generated_at":"2026-10-02T17:35:04.001Z","licence":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/","attribution":"TOLL, with a link to the page cited"},"page":"https://tollindex.com/e/api-magentlab-com-api-calc-slicc-sle-bbab8b","pinned_page":"https://tollindex.com/e/api-magentlab-com-api-calc-slicc-sle-bbab8b/at/2026-10-02T12-31Z","pinned":false,"method":"https://tollindex.com/ledger/method","snapshot_at":"2026-10-02T12:31:46.748Z","snapshot_stamp":"2026-10-02T12-31Z","endpoint":{"slug":"api-magentlab-com-api-calc-slicc-sle-bbab8b","canonical_url":"https://api.magentlab.com/api/calc/slicc_sle","resource":"https://api.magentlab.com/api/calc/slicc_sle","http_method":"POST","type":"http","x402_version":2,"registries":["cdp"],"primary_registry":"cdp","curated_by_coinbase":false,"description":"SLICC 2012 SLE classification (Petri Table 3). classified iff biopsy-proven lupus nephritis plus ANA or anti-dsDNA, or at least four criteria including at least one clinical and one immunologic. 11 clinical and 6 immunologic caller flags. Direct Coombs counts only in the absence of hemolytic anemia. Criteria need not be concurrent. Not a diagnosis. Not 1997 ACR. Not 2019 EULAR/ACR. magent does not examine skin, assay serologies, or read a biopsy.","service_name":"magent","declared_category":null,"declared_tags":["slicc","sle","lupus","classification","emergency"],"route_template":null,"registry_updated":"2026-09-28T14:49:19.743Z"},"derived":{"note":"fields no registry supplies; TOLL derives them and marks them derived on the page","title":"calc slicc sle","category":"inference","first_observed_by_toll":"2026-09-28T13:51:25.436Z","last_observed_by_toll":"2026-10-02T12:31:46.748Z","observation_began":"2026-09-10"},"presence":{"listed_now":true,"first_absent_at":null,"delisting_confirmed_at":null,"events":[{"registry":"cdp","at":"2026-09-28T13:51:25.437Z","event":"listed"}]},"accepts":[{"registry":"cdp","ordinal":0,"network":"eip155:8453","asset":"0x833589fcd6edb6e08f4c7c32d4f71b54bda02913","asset_name":"USD Coin","symbol":"USDC","decimals":6,"amount_display":"0.005 USDC","amount_units":0.005,"decimals_known":true,"pay_to":"0x836Be278f1739fB4308091cD1852F7971Bc19Ee2","scheme":"exact"}],"counters":{"observed_at":"2026-10-02T12:31:46.748Z","calls_30d":1,"unique_payers_30d":1,"last_called_at":"2026-09-28T14:49:19.594Z"},"validation":{"latest":{"observed_at":"2026-10-02T16:25:54.023Z","state":"pass","failed_checks":[],"endpoint_http_status":402,"run_id":"daily-2026-10-02"},"uptime":[{"days":7,"observed":5,"passed":5,"ratio":1},{"days":30,"observed":5,"passed":5,"ratio":1},{"days":90,"observed":5,"passed":5,"ratio":1}],"history_90d":[{"observed_at":"2026-10-02T16:25:54.023Z","state":"pass","failed_checks":[],"run_id":"daily-2026-10-02","state_changed":false},{"observed_at":"2026-10-01T09:10:28.483Z","state":"pass","failed_checks":[],"run_id":"daily-2026-10-01","state_changed":false},{"observed_at":"2026-09-30T08:37:20.277Z","state":"pass","failed_checks":[],"run_id":"daily-2026-09-30","state_changed":false},{"observed_at":"2026-09-29T20:44:26.439Z","state":"pass","failed_checks":[],"run_id":"daily-2026-09-29","state_changed":false},{"observed_at":"2026-09-28T16:47:53.224Z","state":"pass","failed_checks":[],"run_id":"new-after-daily-2026-09-28","state_changed":true}]},"seller":{"wallet":"0x836Be278f1739fB4308091cD1852F7971Bc19Ee2","page":"https://tollindex.com/seller/0x836Be278f1739fB4308091cD1852F7971Bc19Ee2","endpoints":844,"hosts":1},"reports":0,"registry_record":{"cdp":[{"tags":["slicc","sle","lupus","classification","emergency"],"type":"http","accepts":[{"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","extra":{"name":"USD Coin","version":"2","paymentFlow":"upfront","resourceUrl":"https://api.magentlab.com/api/calc/slicc_sle","assetTransferMethod":"eip3009"},"payTo":"0x836Be278f1739fB4308091cD1852F7971Bc19Ee2","amount":"5000","scheme":"exact","network":"eip155:8453","maxTimeoutSeconds":600}],"quality":{"lastCalledAt":"2026-09-28T14:49:19.594Z","l30DaysTotalCalls":1,"l30DaysUniquePayers":1},"resource":"https://api.magentlab.com/api/calc/slicc_sle","extensions":{"bazaar":{"info":{"input":{"body":{"items":[{"ana":true,"renal":false,"anti_sm":false,"serositis":false,"synovitis":true,"anti_dsdna":true,"neurologic":false,"direct_coombs":false,"low_complement":false,"antiphospholipid":false,"hemolytic_anemia":false,"thrombocytopenia":false,"nonscarring_alopecia":false,"oral_or_nasal_ulcers":true,"acute_cutaneous_lupus":true,"biopsy_lupus_nephritis":false,"chronic_cutaneous_lupus":false,"leukopenia_or_lymphopenia":false},{"ana":true,"renal":false,"anti_sm":false,"serositis":false,"synovitis":true,"anti_dsdna":true,"neurologic":false,"direct_coombs":false,"low_complement":false,"antiphospholipid":false,"hemolytic_anemia":false,"thrombocytopenia":false,"nonscarring_alopecia":false,"oral_or_nasal_ulcers":true,"acute_cutaneous_lupus":true,"biopsy_lupus_nephritis":false,"chronic_cutaneous_lupus":false,"leukopenia_or_lymphopenia":false}]},"type":"http","method":"POST"},"output":{"type":"json","example":{"path":"/api/calc/slicc_sle","count":2,"items":[{"formula":"slicc_sle","citation":{"id":"petri-2012","doi":"10.1002/art.34473","pmid":"22553077","title":"Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus","source":"Arthritis Rheum. 2012;64(8):2677-2686","authors":"Petri M, Orbai AM, Alarcón GS, Gordon C, Merrill JT, Fortin PR, Bruce IN, Isenberg D, Wallace DJ, Nived O, Sturfelt G, Ramsey-Goldman R, Bae SC, Hanly JG, Sánchez-Guerrero J, Clarke A, Aranow C, Manzi S, Urowitz M, Gladman D, Kalunian K, Costner M, Werth VP, Zoma A, Bernatsky S, Ruiz-Irastorza G, Khamashta MA, Jacobsen S, Buyon JP, Maddison P, Dooley MA, van Vollenhoven RF, Ginzler E, Stoll T, Peschken C, Jorizzo JL, Callen JP, Lim SS, Fessler BJ, Inanc M, Kamen DL, Rahman A, Steinsson K, Franks AG, Sigler L, Hameed S, Fang H, Pham N, Brey R, Weisman MH, McGwin G, Magder LS"},"classified":true,"disclaimer":"Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.","clinical_count":3,"immunologic_count":2,"formula_expression":"SLICC 2012 SLE classification (Petri Table 3 + classification rule): 11 clinical flags (acute_cutaneous_lupus, chronic_cutaneous_lupus, oral_or_nasal_ulcers, nonscarring_alopecia, synovitis, serositis, renal, neurologic, hemolytic_anemia, leukopenia_or_lymphopenia, thrombocytopenia) and 6 immunologic flags (ana, anti_dsdna, anti_sm, antiphospholipid, low_complement, direct_coombs). clinical_count = count of clinical flags that are true. immunologic_count = count of immunologic flags that are true, except direct_coombs counts only when hemolytic_anemia is false. nephritis_shortcut iff biopsy_lupus_nephritis and (ana or anti_dsdna). classified iff nephritis_shortcut or (clinical_count ≥1 and immunologic_count ≥1 and clinical_count + immunologic_count ≥4). Criteria need not be concurrent. Not a diagnosis. Not 1997 ACR. Not 2019 EULAR/ACR","nephritis_shortcut":false},{"formula":"slicc_sle","citation":{"id":"petri-2012","doi":"10.1002/art.34473","pmid":"22553077","title":"Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus","source":"Arthritis Rheum. 2012;64(8):2677-2686","authors":"Petri M, Orbai AM, Alarcón GS, Gordon C, Merrill JT, Fortin PR, Bruce IN, Isenberg D, Wallace DJ, Nived O, Sturfelt G, Ramsey-Goldman R, Bae SC, Hanly JG, Sánchez-Guerrero J, Clarke A, Aranow C, Manzi S, Urowitz M, Gladman D, Kalunian K, Costner M, Werth VP, Zoma A, Bernatsky S, Ruiz-Irastorza G, Khamashta MA, Jacobsen S, Buyon JP, Maddison P, Dooley MA, van Vollenhoven RF, Ginzler E, Stoll T, Peschken C, Jorizzo JL, Callen JP, Lim SS, Fessler BJ, Inanc M, Kamen DL, Rahman A, Steinsson K, Franks AG, Sigler L, Hameed S, Fang H, Pham N, Brey R, Weisman MH, McGwin G, Magder LS"},"classified":true,"disclaimer":"Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.","clinical_count":3,"immunologic_count":2,"formula_expression":"SLICC 2012 SLE classification (Petri Table 3 + classification rule): 11 clinical flags (acute_cutaneous_lupus, chronic_cutaneous_lupus, oral_or_nasal_ulcers, nonscarring_alopecia, synovitis, serositis, renal, neurologic, hemolytic_anemia, leukopenia_or_lymphopenia, thrombocytopenia) and 6 immunologic flags (ana, anti_dsdna, anti_sm, antiphospholipid, low_complement, direct_coombs). clinical_count = count of clinical flags that are true. immunologic_count = count of immunologic flags that are true, except direct_coombs counts only when hemolytic_anemia is false. nephritis_shortcut iff biopsy_lupus_nephritis and (ana or anti_dsdna). classified iff nephritis_shortcut or (clinical_count ≥1 and immunologic_count ≥1 and clinical_count + immunologic_count ≥4). Criteria need not be concurrent. Not a diagnosis. Not 1997 ACR. Not 2019 EULAR/ACR","nephritis_shortcut":false}]}},"iconUrl":"https://api.magentlab.com/favicon.ico"},"schema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"body":{"type":"object","required":["items"],"properties":{"items":{"type":"array","items":{"type":"object","required":["acute_cutaneous_lupus","chronic_cutaneous_lupus","oral_or_nasal_ulcers","nonscarring_alopecia","synovitis","serositis","renal","neurologic","hemolytic_anemia","leukopenia_or_lymphopenia","thrombocytopenia","ana","anti_dsdna","anti_sm","antiphospholipid","low_complement","direct_coombs","biopsy_lupus_nephritis"],"properties":{"ana":{"type":"boolean","description":"ANA above laboratory reference range as assigned by the caller (Petri 2012 Table 3). With biopsy_lupus_nephritis (or anti_dsdna), fulfills the nephritis shortcut. true or false. magent does not assay ANA."},"renal":{"type":"boolean","description":"Renal clinical criterion as assigned by the caller (Petri 2012 Table 3): urine protein-to-creatinine ratio (or 24-hour urine protein) representing 500 mg protein/24 hours, or red blood cell casts. Distinct from biopsy_lupus_nephritis. true or false. magent does not assay urine."},"anti_sm":{"type":"boolean","description":"Antibody to Sm nuclear antigen as assigned by the caller (Petri 2012 Table 3). true or false. magent does not assay anti-Sm."},"serositis":{"type":"boolean","description":"Serositis as assigned by the caller (Petri 2012 Table 3): typical pleurisy >1 day or pleural effusion or pleural rub, or typical pericardial pain >1 day or pericardial effusion or pericardial rub or pericarditis by electrocardiography, in the absence of other causes. true or false. magent does not examine the chest."},"synovitis":{"type":"boolean","description":"Synovitis involving 2 or more joints, characterized by swelling or effusion, or tenderness in 2 or more joints and at least 30 minutes of morning stiffness, as assigned by the caller (Petri 2012 Table 3). true or false. magent does not examine joints."},"anti_dsdna":{"type":"boolean","description":"Anti-dsDNA above laboratory reference range (or >2-fold the reference range if tested by ELISA), as assigned by the caller (Petri 2012 Table 3). true or false. magent does not assay anti-dsDNA."},"neurologic":{"type":"boolean","description":"Neurologic criterion as assigned by the caller (Petri 2012 Table 3): seizures, psychosis, mononeuritis multiplex, myelitis, peripheral or cranial neuropathy, or acute confusional state, in the absence of other known causes. true or false. magent does not examine the nervous system."},"direct_coombs":{"type":"boolean","description":"Direct Coombs’ test as assigned by the caller (Petri 2012 Table 3). Counts toward immunologic_count only when hemolytic_anemia is false. true or false. magent does not run a Coombs test."},"low_complement":{"type":"boolean","description":"Low C3, low C4, or low CH50 as assigned by the caller (Petri 2012 Table 3). true or false. magent does not assay complement."},"antiphospholipid":{"type":"boolean","description":"Antiphospholipid antibody positivity as assigned by the caller (Petri 2012 Table 3): lupus anticoagulant, false-positive rapid plasma reagin, medium- or high-titer anticardiolipin (IgA, IgG, or IgM), or anti-β2-glycoprotein I (IgA, IgG, or IgM). true or false. magent does not assay antiphospholipid antibodies."},"hemolytic_anemia":{"type":"boolean","description":"Hemolytic anemia as assigned by the caller (Petri 2012 Table 3). When true, direct_coombs does not count toward immunologic_count. true or false. magent does not assay hemolysis."},"thrombocytopenia":{"type":"boolean","description":"Thrombocytopenia (<100,000/mm³) at least once in the absence of other known causes, as assigned by the caller (Petri 2012 Table 3). true or false. magent does not assay platelets."},"nonscarring_alopecia":{"type":"boolean","description":"Nonscarring alopecia: diffuse thinning or hair fragility with visible broken hairs, in the absence of other causes, as assigned by the caller (Petri 2012 Table 3). true or false. magent does not examine the scalp."},"oral_or_nasal_ulcers":{"type":"boolean","description":"Oral ulcers (palate, buccal, tongue) or nasal ulcers, in the absence of other causes, as assigned by the caller (Petri 2012 Table 3). true or false. magent does not examine mucosa."},"acute_cutaneous_lupus":{"type":"boolean","description":"Acute cutaneous lupus as assigned by the caller (Petri 2012 Table 3): lupus malar rash (do not count if malar discoid), bullous lupus, toxic epidermal necrolysis variant of SLE, maculopapular lupus rash, photosensitive lupus rash in the absence of dermatomyositis, or subacute cutaneous lupus. true or false. magent does not examine skin."},"biopsy_lupus_nephritis":{"type":"boolean","description":"Biopsy-proven nephritis compatible with SLE as assigned by the caller (Petri 2012 classification rule). With ANA or anti-dsDNA, classifies without four criteria. Distinct from the renal clinical item. true or false. magent does not read a biopsy."},"chronic_cutaneous_lupus":{"type":"boolean","description":"Chronic cutaneous lupus as assigned by the caller (Petri 2012 Table 3): classic discoid (localized or generalized), hypertrophic (verrucous) lupus, lupus panniculitis (profundus), mucosal lupus, lupus erythematosus tumidus, chilblains lupus, or discoid lupus/lichen planus overlap. true or false. magent does not examine skin."},"leukopenia_or_lymphopenia":{"type":"boolean","description":"Leukopenia (<4,000/mm³ at least once) in the absence of other known causes, or lymphopenia (<1,000/mm³ at least once) in the absence of other known causes, as assigned by the caller (Petri 2012 Table 3). true or false. magent does not assay blood counts."}}},"maxItems":25,"minItems":1}},"additionalProperties":false},"type":{"type":"string","const":"http"},"method":{"type":"string","const":"POST"},"headers":{"type":"object","additionalProperties":{"type":"string"}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object"}}}}}}},"description":"SLICC 2012 SLE classification (Petri Table 3). classified iff biopsy-proven lupus nephritis plus ANA or anti-dsDNA, or at least four criteria including at least one clinical and one immunologic. 11 clinical and 6 immunologic caller flags. Direct Coombs counts only in the absence of hemolytic anemia. Criteria need not be concurrent. Not a diagnosis. Not 1997 ACR. Not 2019 EULAR/ACR. magent does not examine skin, assay serologies, or read a biopsy.","lastUpdated":"2026-09-28T14:49:19.743Z","serviceName":"magent","x402Version":2}]}}