{"api":"v1","generated_at":"2026-10-01T02:45:37.873Z","licence":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/","attribution":"TOLL, with a link to the page cited"},"page":"https://tollindex.com/e/api-magentlab-com-api-calc-myeloma-iss-47f3ce","pinned_page":"https://tollindex.com/e/api-magentlab-com-api-calc-myeloma-iss-47f3ce/at/2026-09-30T22-14Z","pinned":false,"method":"https://tollindex.com/ledger/method","snapshot_at":"2026-09-30T22:14:11.940Z","snapshot_stamp":"2026-09-30T22-14Z","endpoint":{"slug":"api-magentlab-com-api-calc-myeloma-iss-47f3ce","canonical_url":"https://api.magentlab.com/api/calc/myeloma_iss","resource":"https://api.magentlab.com/api/calc/myeloma_iss","http_method":"POST","type":"http","x402_version":2,"registries":["cdp"],"primary_registry":"cdp","curated_by_coinbase":false,"description":"Greipp 2005 International Staging System for multiple myeloma. Stage I: serum beta-2 microglobulin <3.5 mg/L and albumin >=3.5 g/dL. Stage III: beta-2 microglobulin >=5.5 mg/L. Stage II: neither I nor III. Returns iss_stage 1/2/3. Not a myeloma diagnosis or treatment choice; not R-ISS (no LDH, no cytogenetics); not trauma ISS. magent does not assay beta-2 microglobulin or albumin.","service_name":"magent","declared_category":null,"declared_tags":["myeloma-iss","myeloma","hematology","staging","calculator"],"route_template":null,"registry_updated":"2026-09-28T15:12:40.346Z"},"derived":{"note":"fields no registry supplies; TOLL derives them and marks them derived on the page","title":"calc myeloma iss","category":"other","first_observed_by_toll":"2026-09-28T13:51:25.436Z","last_observed_by_toll":"2026-09-30T22:14:11.940Z","observation_began":"2026-09-10"},"presence":{"listed_now":true,"first_absent_at":null,"delisting_confirmed_at":null,"events":[{"registry":"cdp","at":"2026-09-28T13:51:25.437Z","event":"listed"}]},"accepts":[{"registry":"cdp","ordinal":0,"network":"eip155:8453","asset":"0x833589fcd6edb6e08f4c7c32d4f71b54bda02913","asset_name":"USD Coin","symbol":"USDC","decimals":6,"amount_display":"0.005 USDC","amount_units":0.005,"decimals_known":true,"pay_to":"0x836Be278f1739fB4308091cD1852F7971Bc19Ee2","scheme":"exact"}],"counters":{"observed_at":"2026-09-30T22:14:11.940Z","calls_30d":1,"unique_payers_30d":1,"last_called_at":"2026-09-28T15:12:40.199Z"},"validation":{"latest":{"observed_at":"2026-09-30T06:39:48.024Z","state":"pass","failed_checks":[],"endpoint_http_status":402,"run_id":"daily-2026-09-30"},"uptime":[{"days":7,"observed":4,"passed":4,"ratio":1},{"days":30,"observed":4,"passed":4,"ratio":1},{"days":90,"observed":4,"passed":4,"ratio":1}],"history_90d":[{"observed_at":"2026-09-30T06:39:48.024Z","state":"pass","failed_checks":[],"run_id":"daily-2026-09-30","state_changed":false},{"observed_at":"2026-09-29T18:59:06.831Z","state":"pass","failed_checks":[],"run_id":"daily-2026-09-29","state_changed":false},{"observed_at":"2026-09-28T16:55:24.583Z","state":"pass","failed_checks":[],"run_id":"daily-2026-09-28","state_changed":false},{"observed_at":"2026-09-28T16:41:26.241Z","state":"pass","failed_checks":[],"run_id":"new-after-daily-2026-09-28","state_changed":true}]},"seller":{"wallet":"0x836Be278f1739fB4308091cD1852F7971Bc19Ee2","page":"https://tollindex.com/seller/0x836Be278f1739fB4308091cD1852F7971Bc19Ee2","endpoints":844,"hosts":1},"reports":0,"registry_record":{"cdp":[{"tags":["myeloma-iss","myeloma","hematology","staging","calculator"],"type":"http","accepts":[{"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","extra":{"name":"USD Coin","version":"2","paymentFlow":"upfront","resourceUrl":"https://api.magentlab.com/api/calc/myeloma_iss","assetTransferMethod":"eip3009"},"payTo":"0x836Be278f1739fB4308091cD1852F7971Bc19Ee2","amount":"5000","scheme":"exact","network":"eip155:8453","maxTimeoutSeconds":600}],"quality":{"lastCalledAt":"2026-09-28T15:12:40.199Z","l30DaysTotalCalls":1,"l30DaysUniquePayers":1},"resource":"https://api.magentlab.com/api/calc/myeloma_iss","extensions":{"bazaar":{"info":{"input":{"body":{"items":[{"albumin_g_l":40,"albumin_g_dl":4,"beta2_microglobulin_mg_l":2},{"albumin_g_l":40,"albumin_g_dl":4,"beta2_microglobulin_mg_l":2}]},"type":"http","method":"POST"},"output":{"type":"json","example":{"path":"/api/calc/myeloma_iss","count":2,"items":[{"formula":"myeloma_iss","citation":{"id":"greipp-2005","doi":"10.1200/JCO.2005.04.242","pmid":"15809451","title":"International staging system for multiple myeloma","source":"J Clin Oncol. 2005;23(15):3412-3420","authors":"Greipp PR, San Miguel J, Durie BGM, Crowley JJ, Barlogie B, Bladé J, Boccadoro M, Child JA, Avet-Loiseau H, Kyle RA, Lahuerta JJ, Ludwig H, Morgan G, Powles R, Shimizu K, Shustik C, Sonneveld P, Tosi P, Turesson I, Westin J"},"iss_stage":1,"disclaimer":"Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.","albumin_g_dl":4,"iss_stage_label":"I","formula_expression":"ISS stage I: beta2_microglobulin_mg_l < 3.5 AND albumin_g_dl >= 3.5; stage III: beta2_microglobulin_mg_l >= 5.5; stage II: neither I nor III (Greipp 2005)","beta2_microglobulin_mg_l":2},{"formula":"myeloma_iss","citation":{"id":"greipp-2005","doi":"10.1200/JCO.2005.04.242","pmid":"15809451","title":"International staging system for multiple myeloma","source":"J Clin Oncol. 2005;23(15):3412-3420","authors":"Greipp PR, San Miguel J, Durie BGM, Crowley JJ, Barlogie B, Bladé J, Boccadoro M, Child JA, Avet-Loiseau H, Kyle RA, Lahuerta JJ, Ludwig H, Morgan G, Powles R, Shimizu K, Shustik C, Sonneveld P, Tosi P, Turesson I, Westin J"},"iss_stage":1,"disclaimer":"Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.","albumin_g_dl":4,"iss_stage_label":"I","formula_expression":"ISS stage I: beta2_microglobulin_mg_l < 3.5 AND albumin_g_dl >= 3.5; stage III: beta2_microglobulin_mg_l >= 5.5; stage II: neither I nor III (Greipp 2005)","beta2_microglobulin_mg_l":2}]}},"iconUrl":"https://api.magentlab.com/favicon.ico"},"schema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"body":{"type":"object","required":["items"],"properties":{"items":{"type":"array","items":{"type":"object","required":["beta2_microglobulin_mg_l"],"properties":{"albumin_g_l":{"type":"number","description":"Serum albumin in g/L (10-60). Converted as g/dL = g/L / 10. Provide this or albumin_g_dl, not both."},"albumin_g_dl":{"type":"number","description":"Serum albumin in g/dL (1-6). Provide this or albumin_g_l, not both. Greipp 2005 stages use g/dL. Stage I requires albumin >= 3.5 when Sβ2M < 3.5. Ignored when Sβ2M >= 5.5."},"beta2_microglobulin_mg_l":{"type":"number","description":"Serum beta-2 microglobulin in mg/L (0.2-40). Greipp 2005 Sβ2M. Stage I requires < 3.5; stage III when >= 5.5. magent does not assay beta-2 microglobulin."}}},"maxItems":25,"minItems":1}},"additionalProperties":false},"type":{"type":"string","const":"http"},"method":{"type":"string","const":"POST"},"headers":{"type":"object","additionalProperties":{"type":"string"}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object"}}}}}}},"description":"Greipp 2005 International Staging System for multiple myeloma. Stage I: serum beta-2 microglobulin <3.5 mg/L and albumin >=3.5 g/dL. Stage III: beta-2 microglobulin >=5.5 mg/L. Stage II: neither I nor III. Returns iss_stage 1/2/3. Not a myeloma diagnosis or treatment choice; not R-ISS (no LDH, no cytogenetics); not trauma ISS. magent does not assay beta-2 microglobulin or albumin.","lastUpdated":"2026-09-28T15:12:40.346Z","serviceName":"magent","x402Version":2}]}}